Bacopa Monnieri

The Clinical Research & Resources

Bacopa is a great neurotonic, immuno-modulator, adaptogen, tranquilizing, memory and learning enhancing, cerebral activator, antiulcer, antispasmodic, anti-asthmatic ayurvedic herb. Other benefits are anti-allergic, free radicals scavenging effect and as herbal supplement in Epilepsy, anxiety and depression.

Bacopa In Classical Ayurveda Texts

There are several references in Ayurveda's classical text books about B. monnieri.

  1. Charaka Samhita, Disease Management Section, Ch.1

  2. Sushruta Samhita, Sutra Section, Ch. 46

  3. Sushruta Samhita, Disease Management Section, Ch. 28

  4. Chunekar KC. Bhav Prakasa Nighantu (Hindi translation). Chaukhambha Publications, Varanasi, 1960.

Bacopa In Modern Herbal & Ayurveda References

  1. Dravya Guna Vigyana by Priya Vrita Sharma, Vol. 2, Pg. 3-6, Chaukhamba Bharati Academy, 1995.

  2. Indian Materia Medica by Dr K. M. Nadakarni, Vol. 2, Popular Prakashan, Reprint 2000.

  3. Kirtikar, KR.; Basu, BD. In: Kirtikar KR, Basu BD. , editor. Indian Medicinal Plants. II. II. Allahabad, India, Lalit Mohan Basu Publications; 1935.

  4. Chopra RN. Indigenous Drugs of India. 2nd ed. Calcutta, India: U.N. Dhur and Sons: 1958:341.

  5. The Wealth of India: Raw Materials. II-B. New Delhi: Publications and Information Directorate, CSIR, 1950:2–3.

  6. Indian Pharmacopoeia.

  7. Bone K. Clinical Applications of Ayurvedic and Chinese Herbs: Monographs for the Western Herbal Practitioner. Warwick, Queensland: Phytotherapy Press; 1996.

Bacopa Clinical Research Resources

Bacopa As Antioxidant:

  1. Bhattacharya SK, Bhattacharya A, Kumar A, Ghosal S. Antioxidant activity of B. monniera in rat frontal cortex, striatum, and hippocampus. Phytother Res 2000;14:174-179.

Bacopa As Free Radical Scavenger & Preventive Of DNA Damage:

  1. Free radical scavenging capacity and protective effect of B. monniera L. on DNA damage - Phytother Res. 2003

  2. Free radical scavenging capacity and protective effect of B. monniera L. on DNA damage. Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, V.le A. Doria 6, 95125, Catania, Italy. alrusso@unict.it

  3. Elangovan V, Govindasamy S, Ramamoorthy N, Balasubramaanian K. In vitro studies on the anticancer activity of B. monnieri. Fitoterapia 1995;66:211-215.
     

Bacopa's Effect On Brain Functions:

  1. Chronic effects of Brahmi (B. monniera) on human memory.
    Neuropsychopharmacology. 2002 Aug;27(2):279-81.

  2. The chronic effects of an extract of B. monniera (Brahmi) on cognitive function in healthy human subjects.
     Psychopharmacology (Berl) 2001 Aug;156(4):481-4. & at http://www.hort.purdue.edu/newcrop/CropFactSheets/bramhi.html

  3. The acute effects of an extract of B. monniera (Brahmi) on cognitive function in healthy normal subjects.
    Hum Psychopharmacol. 2001 Jun;16(4):345-351.

  4. Effects of a combined extract of Ginkgo biloba and B. monniera on cognitive function in healthy humans- Hum Psychopharmacol. 2004.

  5. Effects of a combined extract of Ginkgo biloba and B. monniera on cognitive function in healthy humans. Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University, Victoria, Australia. pnathan@bsi.swin.edu.au

  6. Mukherjee DG, Dey CD. Clinical trial on Brahmi. I. J Exper Med Sci 1966:10:5-11.

  7. Singh HK, Dhawan BN. Neuropsychopharmacological effects of the Ayurvedic nootropic B. monniera Linn. (Brahmi). Indian J Pharmacol 1997;29:S359-S365.

  8. Russo A, Borrelli F, Campisi A, et al. Nitric oxide-related toxicity in cultured astrocytes: effect of B. monniera. Life Sci 2003;73:1517-1526.

  9. Jain R, Khanna N K, Trehan TN, et al. Antiinflammatory effects of an Ayurvedic preparation, Brahmi Rasayan, in rodents. Indian J Exp Biol 1994;32:633-636.

  10. Sharma R, Chaturvedi C, Tewari PV. Efficacy of B. monnieri in revitalizing intellectual functions in children. J Res Edu Indian Med 1987;Jan-June:1-12.

  11. Ganguly DK, Malhotra CL. Some behavioural effects of an active fraction from Herpestis monniera, Linn. (Brahmi). Ind J Med Res 1967;55:473-482.

  12. Martis G, Rao A. Neuropharmacological activity of Herpestis monniera. Fitoterapia 1992;63:399-404.

  13. Chowdhuri DK, Parmar D, Kakkar P, Shukla R, Seth PK, Srimal RC. Antistress effects of bacosides of B. monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytother Res 2002;16:639-45.

  14. Agrawal A, Gupta U, Dixit SP, Dubey GP. Changes in brain biogenic amines under the influence of an Ayurvedic drug, Brahmi, and its effect on discrimination learning. Pharmacopsychoecologia 1993;6(1):15-9.

  15. Shukia B, Khanna NK, Godhwani JL. Effect of Brahmi Rasayan on the central nervous system. J Ethnopharmacol 1987;21(1):65-74.

Bacopa Ingredients:

  1. Chakravarty AK, Garai S, Masuda K, et al. Bacopasides III-V: three new triterpenoid glycosides from B. monniera. Chem Pharm Bull (Tokyo) 2003;51:215-217.

  2. Hou CC, Lin SJ, Cheng JT, Hsu FL. Bacopaside HI, bacopasaponin G, and bacopasides A, B, and C from B. monniera. J Nat Prod 2002;65:1759-1763.

  3. Mahato SB, Garai S, Chakravarty AK. Bacopasaponins E and F: two jujubogenin bisdesmosides from B. monniera. Phytochemistry 2000;53:711-714.

  4. Chatterji N, Rastorgi RP, Dhar ML. Chemical examination of B. monniera Wettst. Part I: isolation of chemical constituents. Indian J Chem 1963;1:212.

  5. Rastogi S, Pal R, Kulshreshtha DK. Bacoside A3—a triterpenoid saponin from B. monniera. Phytochemistry 1994;36:133–7.

  6. Jain P, Kulshreshtha DK. Bacoside A1, a minor saponin from B. monniera. Phytochemistry 1993;33:449–51.

Bacopa In Alzheimer's Disease:

  1. Enz A, Amstutz R, Boddeke H, et al. Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease. Prog Brain Res 1993;98:431-438.

  2. Bhattacharya SK, Kumar A, Ghosal S. Effect of B. monniera on animal models of Alzheimer's disease and perturbed central cholinergic markers of cognition in rats. In Molecular Aspects of Asian Medicines, ed. by D. V. Silva Sankar. PJD Publications, New York (in press).

Bacopa In Epilepsy:

  1. Evaluation of sedative and anticonvulsant activities of Unmadnashak Ghrita - J Ethnopharmacol. 2004.

  2. Smith DB. Cognitive effects of anti-epileptic drugs. Adv Neurol 1991;55:197-212.

Bacopa In Gastric & Duodenal Ulcers:

  1. Effect of B. monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats.
    Indian J Exp Biol. 2004 Apr;42(4):389-97.

  2. Sairam K, Rao CV, Babu MD, Goel RK. Prophylactic and curative effects of B. monniera in gastric ulcer models. Phytomedicine 2001;8:423430.

Bacopa's Role As Anti-Helicobacter Pylori:

  1. In vitro evaluation of B. monniera on anti-Helicobacter pylori activity and accumulation of prostaglandins.
    Phytomedicine. 2003;10(6-7):523-7.

Bacopa As Adaptogen:

  1. Adaptogenic effect of B. monniera (Brahmi) - Pharmacol Biochem Behav. 2003.

  2. Adaptogenic effect of B. monniera (Brahmi).Division of Pharmacology, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, India. drai@rediffmail.com

Bacopa In Stress, Anxiety & Depression:

  1. Antidepressant activity of standardized extract of B. monniera in experimental models of depression in rats.
    Phytomedicine. 2002 Apr;9(3):207-11.

  2. Antistress effects of bacosides of B. monnieri
    Phytother Res. 2002 Nov;16(7):639-45.

  3. Chowdhuri DK, Pannar D, Kakkar P, et al. Antistress effects of bacosides of B. monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytother Res 2002;16:639-645.

  4. Sharma R, Chaturvedi C, Tewari PV. Efficacy of B. monnieri in revitalizing intellectual functions in children. J Res Edu Indian Med 1987;Jan-June:1-12.

  5. Singh RH, Singh L. Studies on the anti-anxiety effect of the Medyha Rasayana drug, Brahmi (B. monniera Wettst.)--Part 1. J Res Ayur Siddha 1980;1:133-148.

Bacopa As Anti-Fungal Agent:

  1. Phytotoxic and antimicrobial constituents of B. monnieri and Holmskioldia sanguinea - Phytother Res. 2004.
     

Bacopa In Irritable Bowel Syndrome:

  1. Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496503.

Bacopa For Lungs, Heart & Blood Vessels:

  1. Channa S, Dar A, Yaqoob M, et al. Broncho-vasodilatory activity of fractions and pure constituents isolated from B. monniera. J Ethnopharmacol 2003;86:27-35.

  2. Samiulla DS, Prashanth D, Amit A. Mast cell stabilizing activity of B. monnieri. Fitoterapia 2001;72:284-285.

  3. Dar A, Channa S. Calcium antagonistic activity of B. monniera on vascular and intestinal smooth muscles of rabbit and guinea-pig. J Ethnopharmacol 1999;66:167-174.

  4. Dar A, Channa S. Bronchodilatory and cardiovascular effects of an ethanol extract of B. monniera in anaesthetized rats. Phytomedicine 1997;4:319–23.

  5. Dar A, Channa S. Relaxant effect of ethanol extract of B. monniera on trachea, pulmonary artery and aorta from rabbit and guinea-pig. Phytother Res 1997;11:323–5.

Bacopa In Thyroid:

  1.  Kar A, Panda S, Bharti S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol 2002;81:281-285.

Bacopa In Drug Toxicity:

  1. Sumathi T, Nayeem M, Balakrishna K, et al. Alcoholic extract of B. monniera reduces the in vitro effects of morphine withdrawal in guinea-pig ileum. J Ethnopharmacol 2002;82:75-81.

  2. Sumathy T, Subramanian S, Govindasamy S, et al. Protective role of B. monniera on morphine-induced hepatotoxicity in rats. Phytotherapy Res 2002;15:643-645.

  3. Sumathy T, Govindasamy S, Balakrishna K, Veluchamy G. Protective role of B. monniera on morphine-induced brain mitochondrial enzyme activity in rats. Fitoterapia 2002;73:381-385.

  4. Vohora D, Pal SN, Pillai KK. Protection from phenytoin-induced cognitive deficit by B. monniera, a reputed Indian nootropic plant. J Ethnopharmacol 2000;71:383-390.

  5. Russo A, Borrelli F, Campisi A, et al. Nitric oxide-related toxicity in cultured astrocytes: effect of B. monniera. Life Sci 2003;73:1517–26.

Bacopa Monniera

Bacopa Monniera

(Click Image)

Use Bacopa For:

  1. Memory Enhancing.
  2. Aid In Learning Skills.
  3. Stress, Anxiety and Depression.
  4. Children with ADHD.
  5. Visit Bacopa related pages on this site to get more information about this herbal supplement.
  6. You can take one tablet twice or thrice a day or as suggested by qualified herbalist. Each tablet contains 225 mg of extract standardized for 20 % of Bacosides (A+B).

Buying Information:

We recommend the interested visitors to get Bacopa Monniera supplements from this place. This is a good store, with reputable quality and one of the most reasonable price. Get a bottle of 120 tablets.



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Bacopa Benefits As Per Ayurvedic Medicine
Bacopa Dosage & Biochemical Composition
Bacopa -Precautions & Side Effects
About The Plant & Herb Pictures Of Bacopa
Clinical Research Resources About Bacopa
Benefits & Uses Of Brahmi For Memory, Stress, Anxiety & Depression
 Bacopa's Benefits On Systems Other Than Brain & Nerves Functions

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