Guggul

Herbal Medicine Research Resources Of Guggulipid

Guggul is one of the most used and researched ayurvedic herb both in ayurvedic medicine and herbal medicine. Find the clinical trials and research resources about Commiphora mukul to get the lead to further research studies. The resources include Ayurvedic classical book resources as well as modern herbal research work.

1969 To 1980 Clinical Research Resources:

  1. Satyavati GV, Dwarakanath C, Tripathi SN. Experimental studies on the hypocholesterolemic effect of Commiphora mukul. Engl. (Guggul). Indian J Med Res 1969;57:1950-62.
  2. Nityanand S, Kapoor NK. Hypocholesterolemic effect of Commiphora mukul resin (Guggal). Indian J Exp Biol 1971;9:367–77.
  3. Malhotra SC, Ahuja MM, Sundaram KR. Long term clinical studies on the hypolipidaemic effect of Commiphora mukul (Guggulu) and clofibrate. Indian J Med Res 1977;65:390-5.
  4. Kuppurajan K, et al. Effect of guggulu (Commiphora mukul--Engl.) on serum lipids in obese, hypercholesterolemic and hyperlipemic cases. J Assoc Physicians India 1978;26:367-73.
  5. Mester L, Mester M, Nityanand S. Inhibition of platelet aggregation by guggulu steroids. Planta Med 1979;37:367–9.

1980 To 1990 Clinical Research Resources:

  1. Gopal K, Saran RK, Nityanand S et al. Clinical trial of ethyl acetate extract of gum gugulu (gugulipid) in primary hyperlipidemia. J Assoc Physicians India. 1986; 34:249-51.
  2. Satyavati GV. Gum guggul (Commiphora mukul) - The success of an ancient insight leading to a modern discovery. Indian J Med 1988;87:327–35.
  3. Verma SK, Bordia A. Effect of Commiphora mukul (gum guggulu) in patients of hyperlipidemia with special reference to HDL-cholesterol. Indian J Med Res 1988;87:356-60.
  4.  Nityanand S, Srivastava JS, Asthana OP. Clinical trials with gugulipid—a new hypolipidemic agent. J Assoc Phys India 1989;37:323–8.

1990 To 2000 Clinical Research Resources:

  1. Fackelmann, K. 1991. Grapefruit juice gives drug an added punch. Science News 139(Feb. 9):85.
  2. Singh RP, Singh R, Ram P, et al. Use of Pushkar-Guggul, an indigenous anti-ischemic combination, in the management of ischemic heart disease. Int J Pharm 1993;31(2):147-160.
  3. Dalvi, S.S., et al. 1994. Effect of gugulipid on bioavailability of diltiazem and propranolol. Journal of the Association of Physicians of India 42(June):454. Abstract available at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
    cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7852226    .
  4. Thappa DM, Dogra J. Nodulocystic acne: oral gugulipid versus tetracycline. J Dermatol 1994;21:729–31.
  5. Singh, R.B., M.A. Niaz, and S. Ghosh. 1994. Hypolipidemic and antioxidant effects of Commiphora mukul as an adjunct to dietary therapy in patients with hypercholesterolemia. Cardiovascular Drugs and Therapy 8(August):659-664. Abstract available at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
    cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7848901    .
  6. Bhatt AD, Dalal DG, Shah SJ, et al. Conceptual and methodologic challenges of assessing the short-term efficacy of guggulu in obesity: data emergent from a naturalistic clinical trial. J Postgrad Med 1995;41(1):5-7.
  7. Gaur SP, Garg RK, Kar AM, et al. Gugulipid, a new hypolipidaemic agent, in patients of acute ischaemic stroke: effect on clinical outcome, platelet function and serum lipids. Asia Pacif J Pharm 1997;12:65-69.
  8. Singh K, Chander R, Kapoor NK. Guggulsterone, a potent hypolipidaemic, prevents oxidation of low density lipoprotein. Phytother Res 1997;11:291–4.
  9. Brown D, Austin S. Hyperlipidemia and Prevention of Coronary Artery Disease. Seattle, WA: NPRC, 1997, 4–6.
  10. Altern Med Rev 1998 Dec;3(6):422-31 Miller AL - Botanical influences on cardiovascular disease.
  11. Verma SK, Bordia A. Effect of Commiphora mukul (gum guggulu) in patients of hyperlipidemia with special reference to HDL-cholesterol. Indian J Med Res. 1988; 87:356-60.
  12. Agarwal RC, Singh SP, Saran RK et al. Clinical trial of gugulipid -- a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res. 1986; 84:626-34.
  13. Antonio J, Colker CM, Torina GC, et al. Effects of a standardized guggulsterone phosphate supplement on body composition in overweight adults: a pilot study. Curr Ther Res 1999;60:220-227.
  14.  DerMarderosian A, editor. The Review of Natural Products. St. Louis: Facts and Comparisons; 1999.
  15. McDermott JH. Complementary lipid-lowering therapies. Am J Health-Syst Pharm. 1999; 56:1668-71.
  16. Ghorai M, Mandal SC, Pal M et al. A comparative study on hypocholesterolaemic effect of allicin, whole germinated seeds of bengal gram and guggulipid of gum guggulu. Phytother Res. 2000; 14:200-2.
  17. Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 2000;71:23-43.

2000 Onwards Resources:

  1. Singh BB, Mishra L, Aquilina N, et al. Usefulness of guggul (Commiphora mukul) for osteoarthritis of the knee: an experimental case study. Altern Ther Health Med 2001;7(2):120, 112-114.
  2. Barone, G.W., et al. 2001. Herbal supplements: A potential for drug interactions in transplant recipients. Transplantation 71(Jan. 27):239-241. Abstract.
  3. Caron MF, White CM. Evaluation of the antihyperlipidemic properties of dietary supplements. Pharmacotherapy. 2001; 21:481-7.
  4. Urizar, N.L. . . . and D.D. Moore. 2002. A natural product that lowers cholesterol as an antagonist ligand for FXR. Science 296(May 31):1703-1706. Available at http://www.sciencemag.org/cgi/content/full/296/5573/1703.
  5. 2002. Natural cholesterol fighter shows the way. Baylor College of Medicine press release. Dec. 2. Available at http://www.fromthelab.net/vol01/is4/02dec_b.htm#3.
  6. Szapary, P.O., et al. 2003. Guggulipid for the treatment of hypercholesterolemia: A randomized controlled trial. Journal of the American Medical Association 290(Aug. 13):765-772. Available at http://jama.ama-assn.org/cgi/content/full/290/6/765.
    Philippe O. Szapary
    Division of General Internal Medicine
    Department of Medicine
    University of Pennsylvania
    1222 Blockley Hall
    423 Guardian Drive
    Philadelphia, PA 19104-6021
  7. Markowitz, J.S., et al. 2003. Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme. Journal of the American Medical Association 290(Sept. 17):1500-1504. Available at http://jama.ama-assn.org/cgi/content/full/290/11/1500.
    John S. Markowitz
     Medical University of South Carolina
     Institute of Psychiatry
     Room 246 North
     Laboratory of Drug Disposition and Pharmacogenetics
     67 President Street
     Charleston, SC 29425

  8. 2003. Herbal lottery. Science News 163(June 7):359-361. Available at http://www.sciencenews.org/articles/20030607/bob8.asp.

  9. Urizar NL, Moore DD. Gugulipid: a natural cholesterol-lowering agent. Ann Rev Nutr. 2003; 23:303-13.

  10. Bianchi A, Cantu P, Firenzuoli F, et al. Rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent. Ann Pharmacother 2004;Jul-Aug, 38(7-8):1222-1225.
  11. Brobst, D.E. . . . and J.L. Staudinger. 2004. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. Journal of Pharmacology and Experimental Therapeutics 310(August):528-535. Abstract available at http://jpet.aspetjournals.org/cgi/content/abstract/310/2/528.
  12. Raloff, J. 2004. We're very supplemented. Science News Online (Aug. 28). Available at http://www.sciencenews.org/articles/20040828/food.asp.
  13. Staudinger, J. The Journal of Pharmacology and Experimental Therapeutics, August 2004; vol 310: pp 528-535. News release, University of Kansas.
     Jeffrey L. Staudinger
    Department of Pharmacology and     Toxicology
    University of Kansas
    Malott Hall, Room 5044A
    1251 Wescoe Hall Drive
    Lawrence, KS 66045-7582
  14. Dan E, et al. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. JPET 2004;310:528-535.
  15. Jellin JM, Gregory PJ, Batz F et al. Guggul. Therapeutic research faculty. Natural Medicines Comprehensive Database. www.naturaldatabase.com (accessed 2004 Jun 24).
  16. DerMarderosian A, Beutler JA, eds. Facts and comparisons: the review of natural products. St. Louis: Wolters Kluwer; 2004.

Guggul

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Guggul

Use Guggul For:

  1. Obesity. Excercise & take moderate diet along with it.
  2. For Increased Cholesterol level in blood. Prevent hardening of arteries.
  3. For Acne with pustule containing pus pockets.
  4. For Arthritis.
  5. Use one vegicap twice or thrice a day with water after food. Each vegicap has 425 mg of dried extract, standardized with standardized with 6% Guggulsterones E & Z.

Buying Information:

We recommend the interested visitors to get Guggul Or Commiphora mukul supplements from this place. This is a good store, with reputable quality and one of the most reasonable price. Get a pack of 60 vegicaps.




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Guggul Benefits
Adjuvants Of Guggul
Guggul Side Effects
Guggul In Ayurvedic Medicine
Guggulu History & Various Types
Guggul - Clinical Research & Resources
Guggul Based Ayurvedic Formulations (1)
Guggulipid - Guggul Gum Purification In Ayurveda
Guggul gum  - The Extensive & Interesting Names
Ayurvedic properties, phytochemistry & dosage of Guggul


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